Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417614 | 0.84 | RAB9A (0.57) | NPC1RAB9AEGFRSRCBAZ2B | |
| SCHEMBL12417622 | 0.73 | BRD4 (0.42) | NPC1RAB9AEGFRSRCBRD4 | |
| SCHEMBL14624286 | 0.70 | RAB9A (0.57) | NPC1RAB9ATSHRKDM4EGAA | |
| SCHEMBL12417624 | 0.70 | RAB9A (0.60) | NPC1RAB9ASRCTSHRKDM4E | |
| SCHEMBL12417627 | 0.70 | KDM4E (0.40) | NPC1RAB9ABAZ2BTSHRKDM4E | |
| SCHEMBL23484386 | 0.70 | CYP3A4 (0.56) | TSHRKDM4EGAAHSD17B10MAPT | |
| SCHEMBL12417615 | 0.68 | RAB9A (0.46) | NPC1RAB9ATSHRKDM4EGAA | |
| SCHEMBL12417640 | 0.68 | ALDH1A1 (0.41) | TSHRKDM4EGAAHTTHSD17B10 | |
| SCHEMBL12417620 | 0.68 | TSHR (0.40) | NPC1RAB9AEGFRSRCTSHR | |
| SCHEMBL12417639 | 0.67 | ALDH1A1 (0.46) | NPC1RAB9ATSHRKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342683-A | Azo dyes with carboxyl polyalkyleneoxy chain moiety | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-03 | — | — | US | disclosed |
| US-4250089-A | Process for diazotizing aromatic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-10 | — | — | US | disclosed |