Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379512 | 0.82 | LMNA (0.55) | MEN1ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL11228468 | 0.82 | LMNA (0.55) | MEN1ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL11249182 | 0.81 | MAPT (0.49) | MEN1ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL11225151 | 0.81 | MAPT (0.42) | MEN1ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL11230130 | 0.79 | CYP3A4 (0.50) | MEN1ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL11227170 | 0.79 | MEN1 (0.45) | MEN1ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL11227184 | 0.79 | MEN1 (0.45) | MEN1ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL11235612 | 0.74 | MAPT (0.45) | MEN1ALDH1A1KMT2ASLC6A4MAPT | |
| SCHEMBL15286334 | 0.73 | MAPT (0.44) | MEN1KMT2ASLC6A4MAPTHTT | |
| SCHEMBL15286330 | 0.73 | MAPT (0.44) | MEN1KMT2ASLC6A4MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357338-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4309434-A | Combating fungi with 1-(2-chlorophenyl)-1-(2-chlorobenzyloximino)-2-(1,2,4-triazol-1-yl)-ethane | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| US-4264772-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |