Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386202 | 0.87 | HTT (0.53) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11237883 | 0.87 | HTT (0.53) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11240865 | 0.83 | MAPT (0.40) | MAPTHTTLMNAPKMCYP19A1 | |
| SCHEMBL11388927 | 0.83 | MAPT (0.40) | MAPTHTTLMNAPKMCYP19A1 | |
| SCHEMBL11223080 | 0.83 | HTT (0.48) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11229189 | 0.81 | MEN1 (0.47) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11232119 | 0.81 | LMNA (0.56) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11385996 | 0.81 | LMNA (0.56) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11230130 | 0.80 | CYP3A4 (0.50) | MAPTHTTMEN1ALDH1A1KMT2A | |
| SCHEMBL11227170 | 0.80 | MEN1 (0.45) | MAPTHTTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357338-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4309434-A | Combating fungi with 1-(2-chlorophenyl)-1-(2-chlorobenzyloximino)-2-(1,2,4-triazol-1-yl)-ethane | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| US-4264772-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |