SCHEMBL11229286

SCHEMBL11229286

CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.70
MEN1 O00255 2/20 0.70
KMT2A Q03164 2/20 0.70
ALDH1A1 P00352 1/20 0.70
LMNA P02545 1/20 0.70
TP53 P04637 2/20 0.65
KDM4E B2RXH2 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11242923 0.99 MAPT (0.69) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL23493718 0.93 MAPT (0.72) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL23493923 0.92 MAPT (0.68) MAPTMEN1KMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL11245071 0.91 MAPT (0.69) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL31307860 0.91 MAPT (0.72) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL23493688 0.91 MAPT (0.72) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL16797455 0.90 ALDH1A1 (0.71) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL11245876 0.89 ATP4A (0.68) MAPTMEN1KMT2AALDH1A1LMNA
SCHEMBL25394740 0.89 MAPT (0.75) MAPTMEN1KMT2AALDH1A1LMNA
Hydrochloric Acid SCHEMBL11251093 0.89 MAPT (0.70) MAPTMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343804-A 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds A. H. ROBINS COMPANY, INC. (US) 1982-08-10 US disclosed