Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229287 | 1.00 | LMNA (0.57) | LMNAALDH1A1SMN1; SMN2XBP1TUBB4A | |
| Hydrochloric Acid SCHEMBL11768981 | 0.98 | LMNA (0.56) | LMNAALDH1A1SMN1; SMN2XBP1TUBB4A | |
| Hydrochloric Acid SCHEMBL11768975 | 0.98 | LMNA (0.56) | LMNAALDH1A1SMN1; SMN2XBP1TUBB4A | |
| SCHEMBL10662338 | 0.92 | LMNA (0.66) | LMNAALDH1A1SMN1; SMN2XBP1MAPT | |
| SCHEMBL10662351 | 0.92 | LMNA (0.66) | LMNAALDH1A1SMN1; SMN2XBP1MAPT | |
| Hydrochloric Acid SCHEMBL11769085 | 0.91 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2XBP1MAPT | |
| Hydrochloric Acid SCHEMBL11768006 | 0.91 | LMNA (0.64) | LMNAALDH1A1SMN1; SMN2XBP1MAPT | |
| SCHEMBL19449618 | 0.88 | LMNA (0.48) | LMNAALDH1A1SMN1; SMN2XBP1TUBB4A | |
| SCHEMBL16224319 | 0.88 | LMNA (0.48) | LMNAALDH1A1SMN1; SMN2XBP1TUBB4A | |
| Robenidine SCHEMBL6729906 | 0.87 | SMN1; SMN2 (0.53) | LMNAALDH1A1SMN1; SMN2XBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | claimed |
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |