SCHEMBL11229318

SCHEMBL11229318

Cc1nc(C(=O)Cl)sc1C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.39
RAB9A P51151 9/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
NPC1 O15118 7/20 0.36
PKM P14618 2/20 0.36
MAPT P10636 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
RXFP1 Q9HBX9 1/20 0.33
FFAR2 O15552 1/20 0.33
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267607 0.80 ALDH1A1 (0.44) RAB9ASMN1; SMN2POLBALDH1A1HPGD
SCHEMBL569821 0.79 NOS1 (0.41) NOS1RAB9ASMN1; SMN2POLBALDH1A1
SCHEMBL11833656 0.79 ALDH1A1 (0.42) NOS1RAB9ASMN1; SMN2ALDH1A1HPGD
SCHEMBL2677906 0.77 NOS1 (0.44) NOS1RAB9ASMN1; SMN2POLBALDH1A1
SCHEMBL8682295 0.77 HDAC6 (0.36) NOS1RAB9ASMN1; SMN2POLBNPC1
SCHEMBL12179254 0.76 ALDH1A1 (0.46) NOS1RAB9ASMN1; SMN2POLBALDH1A1
SCHEMBL23835836 0.74 NOS1 (0.37) NOS1RAB9ASMN1; SMN2POLBALDH1A1
SCHEMBL13819563 0.74 ALDH1A1 (0.47) NOS1RAB9ASMN1; SMN2ALDH1A1HPGD
SCHEMBL4878415 0.72 MAPT (0.40) NOS1RAB9ASMN1; SMN2POLBALDH1A1
SCHEMBL14844522 0.72 ALDH1A1 (0.50) NOS1RAB9ASMN1; SMN2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4326065-A PLASTICS, VARNISHES, POLYESTERS EASTMAN KODAK COMPANY (US) 1982-04-20 US disclosed
US-4251433-A BENZOTRIAZOLE DERIVATIVES; FOR POLYMERS EASTMAN KODAK COMPANY (US) 1981-02-17 US disclosed
US-4236013-A ADDITIVES FOR POLYMERS EASTMAN KODAK COMPANY (US) 1980-11-25 US disclosed
US-4137235-A ULTRAVIOLET STABILIZERS IN POLYMERIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1979-01-30 US disclosed
US-4116928-A Heterocylic ester, ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed