Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433422 | 0.90 | CYP2C19 (0.40) | HSD17B10LMNACYP2C19 | |
| SCHEMBL2344965 | 0.82 | RECQL (0.37) | HSD17B10CYP2C19EPHX1KEAP1NFE2L2 | |
| SCHEMBL2335573 | 0.80 | EPHX1 (0.34) | HSD17B10EPHX1KEAP1NFE2L2SSTR4 | |
| SCHEMBL28107685 | 0.80 | CYP2D6 (0.41) | HSD17B10LMNACYP2C19EPHX1KEAP1 | |
| SCHEMBL3147437 | 0.78 | SSTR4 (0.36) | HSD17B10EPHX1KEAP1NFE2L2SSTR4 | |
| SCHEMBL27489829 | 0.78 | KDM4E (0.39) | HSD17B10LMNAEPHX1KEAP1NFE2L2 | |
| SCHEMBL28785379 | 0.77 | EPHX1 (0.33) | HSD17B10EPHX1KEAP1NFE2L2SSTR4 | |
| SCHEMBL432459 | 0.76 | CCR2 (0.37) | HSD17B10EPHX1KEAP1NFE2L2SSTR4 | |
| SCHEMBL3271255 | 0.76 | CYP1A2 (0.39) | EPHX1SSTR4CHRM2CHRM4CHRM1 | |
| SCHEMBL28103582 | 0.74 | EPHX1 (0.35) | EPHX1KEAP1NFE2L2SSTR4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347379-A | REACTING AN ALCOHOL OF THIOL, A HALOFORM, ALKALI METAL HYDROXIDE, AND PHASE TRANSFER AGENT | THE B. F. GOODRICH COMPANY (US) | 1982-08-31 | — | — | US | disclosed |