Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10482083 | 0.84 | HTR2A (0.53) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL11095176 | 0.84 | FFAR1 (0.65) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL11222733 | 0.83 | FFAR1 (0.66) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL921043 | 0.82 | FFAR1 (0.64) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL12967470 | 0.82 | FFAR1 (0.64) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL921021 | 0.82 | FFAR1 (0.54) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL17042865 | 0.80 | FFAR1 (0.69) | FFAR1MRGPRX4HTR2ASLC6A4KCNH2 | |
| SCHEMBL10969104 | 0.79 | FFAR1 (0.60) | FFAR1HTR2ASLC6A4KCNH2MEN1 | |
| SCHEMBL17085326 | 0.79 | HTR2A (0.43) | FFAR1HTR2ASLC6A4KCNH2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL17042503 | 0.78 | FFAR1 (0.67) | FFAR1MRGPRX4MEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| EP-2913325-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Sinochem Corporation (CN) | 2015-09-02 | — | — | EP | disclosed |
| WO-2014063642-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | 中国中化股份有限公司 (CN) | 2014-05-01 | — | — | WO | disclosed |
| US-4353736-A | CROPS OF BARLEY, WHEAT, CORN, RICE OR COATS | CIBA-GEIGY CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | TYR, GART, LRRK2 | FFAR1 3670/4885MRGPRX4 2561/4885HTR2A 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.