Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337079 | 0.81 | HMGB1 (0.55) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL11337082 | 0.81 | HMGB1 (0.55) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL11235983 | 0.80 | PIM1 (0.44) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL11233697 | 0.80 | PTPN1 (0.48) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL3248767 | 0.77 | PTGER4 (0.59) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL3248765 | 0.77 | PTGER4 (0.59) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL29004700 | 0.77 | PTGER4 (0.59) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL1039492 | 0.77 | PTPN1 (0.50) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL24074953 | 0.76 | ALDH1A1 (0.48) | PTGER4PTGER3PTGER2KDM4EALDH1A1 | |
| SCHEMBL148268 | 0.76 | MAPT (0.51) | PTGER4PTGER3PTGER2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317917-A | ANTIINFLAMMATORY, ANALGESIC, ANTIBACTERIAL | AUSONIA FARMACEUTICI S.R.L. (IT) | 1982-03-02 | — | — | US | disclosed |