Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075586 | 0.84 | ALOX5 (0.53) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL11337079 | 0.81 | HMGB1 (0.55) | PTPN1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11337082 | 0.81 | HMGB1 (0.55) | PTPN1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11229672 | 0.80 | PTGER4 (0.47) | PTPN1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL11578063 | 0.79 | HSPA5 (0.54) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL11788209 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL11578059 | 0.79 | HSPA5 (0.54) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL148483 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL148484 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1MAPTMEN1RECQL | |
| SCHEMBL3965068 | 0.77 | HSD17B10 (0.41) | PTPN1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317917-A | ANTIINFLAMMATORY, ANALGESIC, ANTIBACTERIAL | AUSONIA FARMACEUTICI S.R.L. (IT) | 1982-03-02 | — | — | US | disclosed |