Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575823 | 0.89 | TAAR1 (0.48) | TAAR1SLC6A2SLC6A3 | |
| SCHEMBL19661348 | 0.82 | ABAT (0.52) | ABATHRH3TAAR1SLC6A2LOXL2 | |
| SCHEMBL21632218 | 0.80 | TAAR1 (0.64) | ABATTAAR1SLC6A2 | |
| SCHEMBL21357615 | 0.80 | TAAR1 (0.64) | ABATTAAR1SLC6A2 | |
| SCHEMBL10876390 | 0.80 | GFER (0.48) | TAAR1SLC6A2LOXL2 | |
| SCHEMBL1048764 | 0.80 | TAAR1 (0.64) | ABATTAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL10616562 | 0.78 | TAAR1 (0.61) | ABATTAAR1SLC6A2 | |
| SCHEMBL1239401 | 0.78 | TRPA1 (0.50) | TAAR1SLC6A2LOXL2 | |
| SCHEMBL10763436 | 0.78 | SLC6A4 (0.67) | TAAR1SLC6A2SLC6A3 | |
| Sulfuric Acid SCHEMBL7639969 | 0.78 | SLC7A5 (0.41) | TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013592-B1 | N,N-DISUBSTITUTED-AMINOMETHYL-PHENYLETHANOLAMINES AND PHARMACEUTICAL FORMULATIONS THEREOF | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| EP-0013592-A1 | N,N-disubstituted-aminomethyl-phenylethanolamines and pharmaceutical formulations thereof | PFIZER INC. (US) | 1980-07-23 | — | — | EP | disclosed |