Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314690 | 0.87 | HDAC6 (0.39) | HTTPOLBHDAC6NPSR1 | |
| SCHEMBL11310121 | 0.87 | HTT (0.44) | GAAHTTMEN1KMT2ACFTR | |
| SCHEMBL11317140 | 0.85 | CFTR (0.43) | CFTRTP53 | |
| SCHEMBL11314738 | 0.84 | HSP90AA1 (0.42) | HTTMEN1KMT2APOLBHDAC6 | |
| SCHEMBL11327193 | 0.83 | CFTR (0.41) | GAAMEN1KMT2ACFTRHDAC6 | |
| SCHEMBL11327162 | 0.83 | CFTR (0.43) | CFTRNPSR1 | |
| SCHEMBL11323663 | 0.82 | PTGIR (0.44) | GAAMEN1KMT2ACFTRTP53 | |
| SCHEMBL11314723 | 0.81 | SMN1; SMN2 (0.43) | MEN1KMT2APOLBHDAC6NPSR1 | |
| SCHEMBL11570874 | 0.81 | S1PR1 (0.37) | HTTMEN1KMT2ACFTRTP53 | |
| SCHEMBL11322957 | 0.80 | NPSR1 (0.43) | HTTMEN1KMT2APOLBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003056-B1 | N-SUBSTITUTED OMEGA-AMINOALKANOYL-OMEGA-AMINOALKANECARBOXYLIC ACIDS, THEIR APPLICATION AND PROCESS FOR THEIR PREPARATION, AND MEDICINES CONTAINING THESE COMPOUNDS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |
| EP-0003056-A1 | N-substituted omega-aminoalkanoyl-omega-aminoalkanecarboxylic acids, their application and process for their preparation, and medicines containing these compounds | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-07-25 | — | — | EP | disclosed |