Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311686 | 0.90 | PTGIR (0.41) | SMN1; SMN2HDAC6ALDH1A1KDM4ENPSR1 | |
| SCHEMBL11314738 | 0.90 | HSP90AA1 (0.42) | SMN1; SMN2HDAC6KMT2AALDH1A1KDM4E | |
| SCHEMBL11314690 | 0.89 | HDAC6 (0.39) | SMN1; SMN2HDAC6ALDH1A1KDM4ENPSR1 | |
| SCHEMBL11321942 | 0.85 | PTGIR (0.39) | SMN1; SMN2HDAC6ALDH1A1KDM4ENPSR1 | |
| SCHEMBL11116763 | 0.85 | HDAC6 (0.43) | SMN1; SMN2HDAC6ALDH1A1KDM4ENPSR1 | |
| SCHEMBL11220562 | 0.85 | HTT (0.44) | SMN1; SMN2HDAC6KMT2AALDH1A1KDM4E | |
| SCHEMBL11220495 | 0.82 | NPSR1 (0.45) | SMN1; SMN2HDAC6KMT2AALDH1A1KDM4E | |
| SCHEMBL11325054 | 0.82 | NPSR1 (0.39) | SMN1; SMN2HDAC6KMT2AALDH1A1KDM4E | |
| SCHEMBL11229708 | 0.81 | GAA (0.45) | HDAC6KMT2ANPSR1LMNAMEN1 | |
| SCHEMBL11326117 | 0.81 | POLB (0.49) | SMN1; SMN2KMT2AMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | claimed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |