Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | UBE2N | P61088 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26831855 | 1.00 | CYP2D6 (0.30) | CYP2D6SPHK1GMNNLMNAPOLB | |
| SCHEMBL11238127 | 0.87 | RIPK1 (0.34) | — | |
| SCHEMBL10211245 | 0.87 | RIPK1 (0.34) | — | |
| SCHEMBL24298351 | 0.87 | RIPK1 (0.34) | — | |
| SCHEMBL26830178 | 0.83 | ALDH1A1 (0.41) | — | |
| SCHEMBL13576434 | 0.83 | ALDH1A1 (0.31) | — | |
| SCHEMBL18269209 | 0.80 | — | — | |
| SCHEMBL14720712 | 0.76 | RIPK1 (0.32) | — | |
| SCHEMBL24298193 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL15686124 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338346-A | Non-nutritive sweetener | THE PROCTER & GAMBLE COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0013044-A1 | L-aspartyl amide derivatives and their use as sweetening agents | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |