Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.42 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454827 | 0.87 | POLB (0.67) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL2022462 | 0.84 | POLB (0.64) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL28160078 | 0.84 | POLB (0.64) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL11240803 | 0.75 | TLR9 (0.48) | POLBKMT2ATLR9MGLLMEN1 | |
| SCHEMBL157324 | 0.74 | MGLL (0.50) | POLBTLR9MGLLMAOAMAOB | |
| SCHEMBL12464402 | 0.73 | POLB (0.52) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL3992123 | 0.73 | POLB (0.52) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL1965970 | 0.70 | POLB (1.00) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL13896437 | 0.70 | POLB (0.54) | POLBKMT2AELANEGAAEHMT2 | |
| SCHEMBL30022123 | 0.70 | POLB (0.54) | POLBKMT2AELANEGAAEHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365068-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1982-12-21 | — | — | US | disclosed |
| US-4280946-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1981-07-28 | — | — | US | disclosed |
| US-4219481-A | Crosslinkable bis-imidyl derivatives | CIBA-GEIGY CORPORATION (US) | 1980-08-26 | — | — | US | disclosed |
| US-4126619-A | CROSSLINKABLE BIS-IMIDYL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |