Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2022462 | 0.97 | POLB (0.64) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL28160078 | 0.97 | POLB (0.64) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL11229948 | 0.87 | POLB (0.54) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL3992123 | 0.84 | POLB (0.52) | POLBKMT2AELANEGAACASP3 | |
| SCHEMBL12464402 | 0.84 | POLB (0.52) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL13896437 | 0.81 | POLB (0.54) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL30022123 | 0.81 | POLB (0.54) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL1965970 | 0.81 | POLB (1.00) | POLBKMT2AELANEMEN1CDC25B | |
| SCHEMBL3204064 | 0.81 | POLB (0.48) | POLBKMT2AELANEMEN1GAA | |
| SCHEMBL29010701 | 0.81 | CES1 (0.55) | POLBGAACASP3MAOACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017081676-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER | PHARMATWOB (IL) | 2017-05-18 | — | — | WO | claimed |
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-13 | — | — | US | claimed |
| US-5049601-A | For polymers | ETHYL CORPORATION (US) | 1991-09-17 | — | — | US | claimed |
| US-11491245-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-11-08 | — | — | US | disclosed |
| CN-109219606-B | Halogen substituted piperidines as orexin receptor modulators | 阿斯利康(瑞典)有限公司 | 2021-10-01 | — | — | CN | disclosed |
| US-20200353104-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-11-12 | — | — | US | disclosed |
| CN-109219606-A | The piperidines that the halogen of orexin receptor regulator replaces | 阿斯利康(瑞典)有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-108362791-A | Phthalimide detection method in a kind of tealeaves | 中国农业科学院茶叶研究所 | 2018-08-03 | — | — | CN | disclosed |
| CN-108117645-A | The poly- fragrant acid imide manufacturing method of one kind and its process units | 梅雪 | 2018-06-05 | — | — | CN | disclosed |
| WO-2017081676-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER | PHARMATWOB (IL) | 2017-05-18 | — | — | WO | disclosed |
| US-9592308-B2 | Method for production of F-18 labeled amyloid beta ligands | PIRAMAL IMAGING SA (CH) | 2017-03-14 | — | — | US | disclosed |
| US-20090107551-A1 | Organic electronic devices using phthalimide compounds | ENERGY, U.S. DEPARTMENT OF | 2009-04-30 | — | — | US | disclosed |
| US-20090107551-A1 | Organic electronic devices using phthalimide compounds | ENERGY, U.S. DEPARTMENT OF | 2009-04-30 | — | — | US | disclosed |
| WO-2007120788-A1 | ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS | THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-10-25 | — | — | WO | disclosed |
| EP-1812028-A2 | HERBAL COMPOSITION PHY906 AND ITS USE IN CHEMOTHERAPY | YALE UNIVERSITY (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006053049-A2 | HERBAL COMPOSITION PHY906 AND ITS USE IN CHEMOTHERAPY | YALE UNIVERSITY (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20050196473-A1 | Herbal composition PHY906 and its use in chemotherapy | KADMON CORPORATION, LLC | 2005-09-08 | — | — | US | disclosed |
| US-4444264-A | PHTHALIMIDE PARTICLES | HALLIBURTON COMPANY (US) | 1984-04-24 | — | — | US | disclosed |
| US-4310461-A | HYPTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-01-12 | — | — | US | disclosed |
| US-3933507-A | LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER | AGFA-GEVAERT, A.G. (DT) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11491245-B2 | Gadolinium chelate compounds for use in magnetic resonance imaging | GLRA1, GLRA3, GLRB | POLB 3836/4885KMT2A 3983/4885ELANE 4048/4885 |
| US-20130149243-A1 | METHOD FOR PRODUCTION OF F-18 LABELED GLUTAMIC ACID DERIVATIVES | GLUL, SLC18A2, SLC1A2 | POLB 3501/4885KMT2A 708/4885ELANE 4502/4885 |
| US-20200353104-A1 | GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | GLRA1, GLRA3, GLRB | POLB 3836/4885KMT2A 3983/4885ELANE 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.