Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229978 | 1.00 | LMNA (0.41) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL18424789 | 1.00 | LMNA (0.41) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL2237340 | 0.87 | LMNA (0.47) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL18425552 | 0.83 | LMNA (0.50) | LMNAALOX15BLMPMP22ACHE | |
| SCHEMBL22712529 | 0.79 | LMNA (0.39) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL20438772 | 0.78 | LMNA (0.44) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL27813040 | 0.77 | LMNA (0.37) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL15148211 | 0.77 | LMNA (0.37) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL3975179 | 0.75 | — | — | |
| SCHEMBL14626285 | 0.73 | TSHR (0.40) | LMNATSHRTHPOFFAR3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358606-A | Esters of phenalkyloxycarbonylamino acids | ZOECON CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |