Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LDHB | P07195 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229978 | 0.87 | LMNA (0.41) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL11229973 | 0.87 | LMNA (0.41) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL18424789 | 0.87 | LMNA (0.41) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL15148211 | 0.82 | LMNA (0.37) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL3975179 | 0.81 | — | — | |
| SCHEMBL14657296 | 0.76 | TSHR (0.35) | LMNAALOX15BLMPMP22LDHA | |
| SCHEMBL18425552 | 0.74 | LMNA (0.50) | LMNAALOX15BLMPMP22ACHE | |
| SCHEMBL9033319 | 0.73 | LDHA (0.47) | LMNAALOX15BLMPMP22LDHA | |
| Oxalic Acid SCHEMBL11065208 | 0.72 | LMNA (0.73) | LMNAALOX15BLMPMP22LDHA | |
| Oxalic Acid SCHEMBL28860992 | 0.72 | LMNA (0.73) | LMNAALOX15BLMPMP22LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |
| CN-108047201-A | Uracil derivative as AXL and c-MET kinase inhibitors | 亚尼塔公司 | 2018-05-18 | — | — | CN | disclosed |
| CN-106029661-B | Pyrazolo [1,5-A ] pyridine derivatives and methods of use thereof | 亚尼塔公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-103958497-B | uracil derivatives as AXL and c-MET kinase inhibitors | 亚尼塔公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-106029661-A | Pyrazolo [1,5-A ] pyridine derivatives and methods of use thereof | 亚尼塔公司 | 2016-10-12 | — | — | CN | disclosed |
| US-8952025-B2 | Multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Ari (US) | 2013-10-10 | — | — | US | disclosed |
| EP-2536690-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | Arizona Board Of Regents (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267546-A1 | Multifunctional Radical Quenchers and Their Uses | SQOR, GSR, GPX4 | LMNA 1653/4885ALOX15 220/4885BLM 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.