Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381248 | 1.00 | CYP19A1 (0.44) | CYP19A1KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11223080 | 0.90 | HTT (0.48) | CYP19A1KDM4EALDH1A1SMN1; SMN2ESR1 | |
| SCHEMBL11231619 | 0.90 | SMN1; SMN2 (0.39) | CYP19A1KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11238684 | 0.86 | KDM4E (0.40) | CYP19A1KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11386202 | 0.84 | HTT (0.53) | CYP19A1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL11237883 | 0.84 | HTT (0.53) | CYP19A1KDM4EALDH1A1MAPTHTT | |
| SCHEMBL11388927 | 0.84 | MAPT (0.40) | CYP19A1SMN1; SMN2DRD4MAPTHTT | |
| SCHEMBL11240865 | 0.84 | MAPT (0.40) | CYP19A1SMN1; SMN2DRD4MAPTHTT | |
| SCHEMBL11232740 | 0.83 | KDM4E (0.41) | CYP19A1KDM4EALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11237894 | 0.81 | KDM4E (0.48) | CYP19A1KDM4EALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357338-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4309434-A | Combating fungi with 1-(2-chlorophenyl)-1-(2-chlorobenzyloximino)-2-(1,2,4-triazol-1-yl)-ethane | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| EP-0004917-B1 | OXIMINO-TRIAZOLYL ETHANES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4264772-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |