Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11388927 | 1.00 | MAPT (0.40) | MAPTHTTCYP19A1DRD4HDAC1 | |
| SCHEMBL11231619 | 0.94 | SMN1; SMN2 (0.39) | MAPTHTTCYP19A1DRD4SMN1; SMN2 | |
| SCHEMBL11237883 | 0.88 | HTT (0.53) | MAPTHTTCYP19A1LMNAPKM | |
| SCHEMBL11386202 | 0.88 | HTT (0.53) | MAPTHTTCYP19A1LMNAPKM | |
| SCHEMBL15286334 | 0.86 | MAPT (0.44) | MAPTHTTCYP19A1HDAC1HDAC6 | |
| SCHEMBL15286330 | 0.86 | MAPT (0.44) | MAPTHTTCYP19A1HDAC1HDAC6 | |
| SCHEMBL11381248 | 0.84 | CYP19A1 (0.44) | MAPTHTTCYP19A1DRD4SMN1; SMN2 | |
| SCHEMBL11229979 | 0.84 | CYP19A1 (0.44) | MAPTHTTCYP19A1DRD4SMN1; SMN2 | |
| SCHEMBL11223080 | 0.83 | HTT (0.48) | MAPTHTTCYP19A1SMN1; SMN2LMNA | |
| SCHEMBL11225151 | 0.83 | MAPT (0.42) | MAPTHTTCYP19A1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357338-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4309434-A | Combating fungi with 1-(2-chlorophenyl)-1-(2-chlorobenzyloximino)-2-(1,2,4-triazol-1-yl)-ethane | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| EP-0004917-B1 | OXIMINO-TRIAZOLYL ETHANES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4264772-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| EP-0004917-A1 | Oximino-triazolyl ethanes, process for their preparation and their use as fungicides | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |