Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894568 | 0.86 | CYP19A1 (0.49) | CYP19A1MAOBPIK3CAPIK3CBPIK3CG | |
| SCHEMBL11241082 | 0.85 | CYP19A1 (0.48) | CYP19A1MEN1KMT2AMAOBPIK3CA | |
| SCHEMBL11231299 | 0.85 | CYP19A1 (0.45) | CYP19A1ALOX12MAOB | |
| SCHEMBL11232796 | 0.84 | CYP19A1 (0.51) | CYP19A1KMT2AMAOB | |
| SCHEMBL10893708 | 0.84 | CYP19A1 (0.54) | CYP19A1MEN1KMT2AALOX15ALOX12 | |
| Hydrochloric Acid SCHEMBL11236478 | 0.84 | CYP19A1 (0.47) | CYP19A1MEN1KMT2AMAOBPIK3CA | |
| Bromide SCHEMBL11239402 | 0.84 | CYP19A1 (0.44) | CYP19A1ALOX12MAOB | |
| SCHEMBL11239544 | 0.82 | TBXAS1 (0.45) | CYP19A1 | |
| SCHEMBL11230658 | 0.82 | CYP19A1 (0.40) | CYP19A1MEN1KMT2AALOX15ADRA2A | |
| SCHEMBL11237227 | 0.82 | TERT (0.39) | CYP19A1MAOBPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |