Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | EGFR | P00533 | 4/20 | 0.55 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.49 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393439 | 0.84 | EGFR (0.66) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL2058767 | 0.84 | EGFR (0.66) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL2029718 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL1711226 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL10733520 | 0.79 | TRPA1 (0.61) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL1711227 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL9361224 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL12173470 | 0.79 | KDM4E (0.65) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL9361219 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR | |
| SCHEMBL8665792 | 0.79 | KDM4E (0.60) | KDM4ELMNAPKMKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359454-A | IN SITU POLYMERIZATION OF METHYL CYANOACRYLATE AND DEGRADATION | WORLD HEALTH ORGANIZATION (CH) | 1982-11-16 | — | — | US | disclosed |