SCHEMBL11230455

SCHEMBL11230455

Cc1ccc(C(=O)c2ccc(O)cc2O)c(O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.57
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
USP2 O75604 1/20 0.56
GAA P10253 1/20 0.56
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56
CA12 O43570 4/20 0.55
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
CA7 P43166 4/20 0.55
CA9 Q16790 4/20 0.55
CA14 Q9ULX7 4/20 0.55
ALDH1A1 P00352 4/20 0.55
TSHR P16473 2/20 0.55
NPC1 O15118 3/20 0.53
RAB9A P51151 2/20 0.53
PDK2 Q15119 2/20 0.53
PDK4 Q16654 2/20 0.53
HSP90AB1 P08238 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758035 0.92 NPC1 (0.56) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL30578000 0.92 NPC1 (0.56) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL29499836 0.91 KMT2A (0.53) CES2KMT2AMEN1USP2GAA
SCHEMBL5709905 0.91 KMT2A (0.53) CES2KMT2AMEN1USP2GAA
SCHEMBL30375427 0.89 KMT2A (0.50) CES2KMT2AMEN1USP2GAA
SCHEMBL5710037 0.89 KMT2A (0.50) CES2KMT2AMEN1USP2GAA
SCHEMBL39507 0.87 CES2 (0.73) CES2KMT2AMEN1USP2GAA
SCHEMBL29357695 0.87 CES2 (0.73) CES2KMT2AMEN1USP2GAA
SCHEMBL28675374 0.86 KMT2A (0.47) CES2KMT2AMEN1USP2GAA
SCHEMBL1101897 0.85 KMT2A (0.68) CES2KMT2AMEN1USP2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687229-B2 Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-4323710-A A NONAQUEOUS SOLVENT OF POLYOXYETHYLENE GLYCOL OR ITS ALKYLATED DERIVATIVES GAF CORPORATION (US) 1982-04-06 US disclosed