Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379925 | 0.83 | GAA (0.41) | LMNATSHRALDH1A1 | |
| SCHEMBL11239489 | 0.81 | LMNA (0.43) | LMNATSHRMAPTALDH1A1 | |
| SCHEMBL423404 | 0.79 | LMNA (0.42) | LMNAPPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL2039271 | 0.78 | GAA (0.46) | TSHRMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL21629430 | 0.77 | LMNA (0.41) | LMNAPPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL11232742 | 0.76 | LMNA (0.37) | LMNAPPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL11232403 | 0.76 | KDM4E (0.33) | MAPTALDH1A1 | |
| SCHEMBL18025607 | 0.74 | — | — | |
| SCHEMBL10142215 | 0.73 | LMNA (0.42) | LMNAPPARGNCOA2NCOA1NPSR1 | |
| SCHEMBL5933090 | 0.73 | LMNA (0.45) | LMNAPPARGNCOA2NCOA1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |