Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239070 | 0.85 | TSHR (0.46) | LMNAHTTMAPTEPHX2TSHR | |
| SCHEMBL11338426 | 0.82 | LMNA (0.50) | LMNAHTTMAPTEPHX2TSHR | |
| SCHEMBL11230486 | 0.81 | LMNA (0.37) | LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL11237465 | 0.80 | CYP1A2 (0.48) | ALDH1A1 | |
| SCHEMBL11233700 | 0.77 | ALDH1A1 (0.40) | LMNAMAPTEPHX2ALDH1A1 | |
| SCHEMBL21396389 | 0.77 | LMNA (0.46) | LMNAHTTMAPTEPHX2TSHR | |
| SCHEMBL11232456 | 0.76 | SIGMAR1 (0.34) | ALDH1A1ALOX15SIGMAR1 | |
| SCHEMBL10820629 | 0.76 | LMNA (0.48) | LMNAHTTMAPTEPHX2TSHR | |
| SCHEMBL11220822 | 0.74 | LMNA (0.47) | LMNAHTTMAPTEPHX2TSHR | |
| SCHEMBL11379764 | 0.74 | LMNA (0.47) | LMNAHTTMAPTEPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |