Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893708 | 0.92 | CYP19A1 (0.54) | CYP19A1PTPN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL11239540 | 0.87 | CYP19A1 (0.39) | CYP19A1PTPN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL11229062 | 0.81 | CYP19A1 (0.38) | CYP19A1PTPN1CYP3A4TP53CYP11B1 | |
| SCHEMBL11231221 | 0.81 | CYP19A1 (0.48) | CYP19A1PTPN1ALOX12MAOB | |
| SCHEMBL11226045 | 0.81 | CYP19A1 (0.40) | CYP19A1LMNAMAOBCYP11B1CYP11B2 | |
| SCHEMBL11228994 | 0.81 | CYP19A1 (0.41) | CYP19A1PTPN1MAPTSMN1; SMN2MEN1 | |
| Bromide SCHEMBL11229202 | 0.81 | CYP19A1 (0.47) | CYP19A1PTPN1ALOX12MAOB | |
| SCHEMBL10856640 | 0.81 | CYP19A1 (0.52) | CYP19A1PTPN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9529868 | 0.80 | CYP19A1 (0.48) | CYP19A1MAOB | |
| SCHEMBL10855526 | 0.79 | CYP19A1 (0.54) | CYP19A1PTPN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |