Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NPR1 | P16066 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241082 | 0.91 | CYP19A1 (0.48) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL11236478 | 0.90 | CYP19A1 (0.47) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11231221 | 0.85 | CYP19A1 (0.48) | CYP19A1CYP17A1PTPN1 | |
| SCHEMBL11226045 | 0.85 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| Bromide SCHEMBL11229202 | 0.84 | CYP19A1 (0.47) | CYP19A1CYP17A1PTPN1 | |
| SCHEMBL9529868 | 0.83 | CYP19A1 (0.48) | CYP19A1 | |
| SCHEMBL11237282 | 0.82 | CYP19A1 (0.37) | CYP19A1 | |
| Hydrochloric Acid SCHEMBL11221160 | 0.81 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL11233256 | 0.81 | CYP17A1 (0.40) | CYP19A1CYP11B1CYP11B2CYP17A1TSHR | |
| SCHEMBL11230668 | 0.81 | CYP19A1 (0.51) | CYP19A1CYP11B1CYP11B2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |