Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230234 | 0.88 | ADRB1 (0.66) | ADRB1ADRB3ADRB2PKMTDP1 | |
| Hydrochloric Acid SCHEMBL11247359 | 0.87 | ADRB1 (0.68) | ADRB1ADRB3ADRB2PKMTDP1 | |
| SCHEMBL11244044 | 0.85 | MAPT (0.69) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7014595 | 0.85 | ADRB1 (0.81) | ADRB1ADRB3ADRB2PKMALDH1A1 | |
| SCHEMBL7014599 | 0.85 | ADRB1 (0.81) | ADRB1ADRB3ADRB2PKMALDH1A1 | |
| Hydrochloric Acid SCHEMBL11230526 | 0.84 | MAPT (0.68) | ADRB1ADRB3ADRB2MEN1KMT2A | |
| SCHEMBL7013581 | 0.83 | ADRB1 (0.71) | ADRB1ADRB3ADRB2PKMALDH1A1 | |
| SCHEMBL9655116 | 0.82 | ADRB1 (0.74) | ADRB1ADRB3ADRB2PKMALDH1A1 | |
| SCHEMBL11237765 | 0.82 | ADRB1 (0.64) | ADRB1ADRB3ADRB2MAPK1MEN1 | |
| SCHEMBL11233869 | 0.82 | ADRB1 (0.64) | ADRB1ADRB3ADRB2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |
| CN-110831584-B | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | ADRB1 129/4885ADRB3 79/4885ADRB2 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.