Sugi Predict

Sugi Predict / Compounds / SCHEMBL11230733

SCHEMBL11230733

SCHEMBL11230733

O=C(O)c1ccc(NCc2ccc3c(c2)OCO3)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.70
▸ MAPT P10636 6/20 0.70
▸ MEN1 O00255 5/20 0.70
▸ KMT2A Q03164 5/20 0.70
▸ LMNA P02545 4/20 0.70
▸ ALOX15 P16050 3/20 0.70
▸ HSD17B10 Q99714 2/20 0.70
▸ USP2 O75604 2/20 0.70
▸ GAA P10253 4/20 0.60
▸ L3MBTL1 Q9Y468 3/20 0.60
▸ ALOX12 P18054 3/20 0.60
▸ MAPK1 P28482 3/20 0.60
▸ HTT P42858 2/20 0.60
▸ SMN1; SMN2 Q16637 2/20 0.60
▸ PDE5A O76074 1/20 0.60
▸ INSR P06213 2/20 0.59
▸ IGF1R P08069 2/20 0.59
▸ SRC P12931 1/20 0.59
▸ KDM4E B2RXH2 3/20 0.59
▸ TDP1 Q9NUW8 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11426003 0.99 ALDH1A1 (0.68) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL11426005 0.86 MEN1 (0.67) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL11432927 0.86 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL14043639 0.86 FFAR1 (0.57) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL11236972 0.82 MAPT (1.00) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL9672474 0.82 MAPT (0.63) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL10057818 0.82 INSR (0.77) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL27720182 0.81 ALDH1A1 (0.67) ALDH1A1KMT2AMAPK1NPC1RAB9A
SCHEMBL11459812 0.81 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2ALMNA
SCHEMBL28302394 0.81 ALDH1A1 (0.65) ALDH1A1MAPTMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4206223-A Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof THE DOW CHEMICAL COMPANY (US) 1980-06-03 — — US claimed
US-4133890-A Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid THE DOW CHEMICAL COMPANY (US) 1979-01-09 — — US claimed
US-4362892-A ARALKYLANILINES, ANTICHOLESTEROL AGENTS BEECHAM GROUP LIMITED (GB) 1982-12-07 — — US disclosed
US-4206145-A ALKANOYL-SUBSTITUTED ARALKYLAMINES BEECHAM GROUP LIMITED (GB) 1980-06-03 — — US disclosed
US-4206223-A Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof THE DOW CHEMICAL COMPANY (US) 1980-06-03 — — US disclosed
US-4206223-A Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof THE DOW CHEMICAL COMPANY (US) 1980-06-03 — — US disclosed
US-4206223-A Method for treating hyperglycemia in mammals using 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid or derivatives thereof THE DOW CHEMICAL COMPANY (US) 1980-06-03 — — US disclosed
US-4133890-A Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid THE DOW CHEMICAL COMPANY (US) 1979-01-09 — — US disclosed
US-4133890-A Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid THE DOW CHEMICAL COMPANY (US) 1979-01-09 — — US disclosed
US-4133890-A Hypolipidemic compositions and method employing derivatives of 4-(((1,3-benzodioxol-5-yl)methyl)amino)benzoic acid THE DOW CHEMICAL COMPANY (US) 1979-01-09 — — US disclosed