Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934363 | 0.83 | KMT2A (0.41) | MEN1KMT2ANR1H2ALOX15TDP1 | |
| SCHEMBL11230760 | 0.79 | TLR9 (0.52) | ALOX15TDP1TYMSALDH1A1PKM | |
| SCHEMBL11516791 | 0.77 | TDP1 (0.40) | MEN1KMT2AALOX15TDP1POLB | |
| SCHEMBL11514963 | 0.75 | KMT2A (0.43) | MEN1KMT2AALOX15TDP1POLB | |
| SCHEMBL11510204 | 0.74 | KMT2A (0.35) | MEN1KMT2ANR1H2ALOX15TDP1 | |
| SCHEMBL11475783 | 0.73 | KMT2A (0.38) | MEN1KMT2AALOX15TDP1POLB | |
| SCHEMBL261766 | 0.71 | TYMS (0.52) | ALOX15TDP1TYMSALDH1A1MAPT | |
| SCHEMBL29351267 | 0.71 | TYMS (0.52) | ALOX15TDP1TYMSALDH1A1MAPT | |
| SCHEMBL2682479 | 0.71 | POLB (0.52) | MEN1KMT2AALOX15POLBRAD51 | |
| SCHEMBL2087097 | 0.70 | TDP1 (0.60) | MEN1KMT2AALOX15TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160081-A | Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins | CIBA-GEIGY CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4131613-A | CURING AGENTS FOR EPOXIDE RESINS | CIBA-GEIGY CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-3979393-A | Imidyl- and isoimidyl-phthalic anhydrides, process for their manufacture and their use for curing epoxide resins | CIBA-GEIGY CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |