Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11229170 | 0.99 | ALOX12 (0.33) | CYP19A1ALOX12ALOX15KDM4EALDH1A1 | |
| SCHEMBL11240152 | 0.97 | ALOX12 (0.34) | CYP19A1ALOX12ALOX15KDM4EALDH1A1 | |
| SCHEMBL11237282 | 0.82 | CYP19A1 (0.37) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11228903 | 0.82 | ALOX12 (0.35) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11239412 | 0.82 | HSP90AA1 (0.38) | CYP19A1ALOX12ALOX15 | |
| Hydrochloric Acid SCHEMBL11221160 | 0.81 | CYP19A1 (0.36) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11226406 | 0.81 | — | — | |
| SCHEMBL11232796 | 0.81 | CYP19A1 (0.51) | CYP19A1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11229815 | 0.80 | — | — | |
| SCHEMBL10859764 | 0.80 | CYP17A1 (0.38) | CYP19A1ALOX15KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |