Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11221160 | 0.99 | CYP19A1 (0.36) | CYP19A1ALOX12HTR1ACYP2D6SLC6A4 | |
| SCHEMBL11228903 | 0.85 | ALOX12 (0.35) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11231221 | 0.82 | CYP19A1 (0.48) | CYP19A1ALOX12 | |
| SCHEMBL11229062 | 0.82 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL11230868 | 0.82 | CYP19A1 (0.33) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11239412 | 0.82 | HSP90AA1 (0.38) | CYP19A1ALOX12ALOX15 | |
| SCHEMBL11231299 | 0.81 | CYP19A1 (0.45) | CYP19A1ALOX12 | |
| SCHEMBL11241082 | 0.81 | CYP19A1 (0.48) | CYP19A1 | |
| Bromide SCHEMBL11229202 | 0.81 | CYP19A1 (0.47) | CYP19A1ALOX12 | |
| Hydrochloric Acid SCHEMBL11229170 | 0.81 | ALOX12 (0.33) | CYP19A1ALOX12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |