Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 10/20 | 0.77 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.63 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122743 | 0.94 | GPR132 (0.76) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1122705 | 0.94 | GPR132 (0.76) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1122747 | 0.93 | GPR132 (0.67) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1123028 | 0.92 | GPR132 (0.71) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1123382 | 0.91 | GAA (0.71) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1123379 | 0.90 | GPR132 (0.95) | GPR132CMKLR2CMKLR1SMPD1PTPN1 | |
| SCHEMBL4893620 | 0.89 | GPR132 (0.69) | GPR132CMKLR2CMKLR1SMPD1GPR139 | |
| SCHEMBL1122813 | 0.88 | GPR132 (0.66) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL27638085 | 0.88 | GPR132 (0.66) | GPR132CMKLR2CMKLR1GAARAB9A | |
| SCHEMBL1122745 | 0.88 | GPR132 (0.66) | GPR132CMKLR2CMKLR1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |