Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.61 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | YAP1 | P46937 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.53 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122839 | 0.96 | GAA (0.68) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1123202 | 0.95 | GAA (0.64) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1123314 | 0.95 | GAA (0.64) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1123642 | 0.95 | GAA (0.67) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1123055 | 0.93 | GAA (0.80) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1122705 | 0.93 | GPR132 (0.76) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1122743 | 0.93 | GPR132 (0.76) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL27658923 | 0.92 | GAA (0.68) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1122576 | 0.92 | GAA (0.68) | GAARAB9AGPR132PPARGERAP2 | |
| SCHEMBL1123158 | 0.91 | GPR132 (0.77) | GAARAB9AGPR132PPARGERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |