Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 15/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034403 | 0.82 | KMT2A (0.33) | P2RX7KMT2ABRD4ADRA2C | |
| SCHEMBL29056176 | 0.77 | GAA (0.40) | — | |
| SCHEMBL6937742 | 0.77 | KMT2A (0.36) | P2RX7KMT2ABRD4ADRA2C | |
| SCHEMBL11243876 | 0.77 | CYP1A2 (0.36) | P2RX7KMT2ABRD4 | |
| SCHEMBL8518990 | 0.76 | GRM2 (0.39) | — | |
| SCHEMBL11156914 | 0.75 | BRD4 (0.44) | P2RX7KMT2ABRD4ADRA2C | |
| SCHEMBL2034992 | 0.75 | KMT2A (0.34) | P2RX7KMT2ABRD4ADRA2C | |
| Hydrochloric Acid SCHEMBL11234410 | 0.74 | — | — | |
| SCHEMBL11219187 | 0.72 | MAOA (0.33) | P2RX7KMT2ABRD4ADRA2C | |
| SCHEMBL9698061 | 0.72 | TSHR (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327098-A | Pharmaceutical compositions useful in the treatment of cardiovascular hypertension and containing 4-substituted-2-iminoimadazolidine compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4327108-A | Methods useful in the treatment of cardiac arrhythmia using 4-substituted-2-iminoimidazolidine compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4327107-A | Method useful in the treatment of sugar cataracts using 4-substituted-2-iminoimidazolidine compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4288447-A | Antihyperglycemic 4-substituted 2-iminoimidazolidine compositions | A. H. ROBINS COMPANY, INC. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4288591-A | ANTIINFLAMMATORY, HYPOTENSIVE, HYPOGLYCEMIC | A. H. ROBINS COMPANY, INC. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4247705-A | HYPOTENSIVE, HYPOGLYCEMIC, ANTIINFLAMMATORY | A. H. ROBINS COMPANY, INC. (US) | 1981-01-27 | — | — | US | disclosed |