Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.52 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.52 |
| ▸ | CYP4Z1 | Q86W10 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.42 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226774 | 0.85 | CYP4F2 (0.55) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 | |
| SCHEMBL846137 | 0.84 | CYP4F2 (0.57) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2ALOX5 | |
| SCHEMBL12780429 | 0.83 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 | |
| SCHEMBL6288506 | 0.79 | CYP4F2 (0.70) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 | |
| SCHEMBL13791513 | 0.78 | NPC1 (0.55) | NPC1RAB9APAX8JAK2MLYCD | |
| SCHEMBL6286441 | 0.78 | CYP4F2 (0.72) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 | |
| SCHEMBL10206072 | 0.78 | CYP4F2 (0.77) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2ALOX5 | |
| SCHEMBL11585344 | 0.77 | THRA (0.51) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 | |
| SCHEMBL13791114 | 0.76 | RAB9A (0.53) | NPC1RAB9APAX8JAK2MLYCD | |
| SCHEMBL68902 | 0.76 | CYP4F2 (0.85) | CYP4F2CYP4A11CYP4Z1ALOX5CYP4F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |