Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | NOS2 | P35228 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5397302 | 0.87 | SLC6A2 (0.58) | SLC6A2SLC6A4NOS2CYP2D6TSHR | |
| Phenylacetic Acid SCHEMBL145669 | 0.85 | KDM4E (0.55) | SLC6A4CNR2SLC6A9 | |
| SCHEMBL32660768 | 0.80 | SLC6A2 (0.58) | SLC6A2SLC6A4AKR1B1SLC6A9SLC6A3 | |
| Oxalic Acid SCHEMBL7311161 | 0.78 | SLC6A2 (0.59) | SLC6A2SLC6A4NOS2CYP2D6SLC6A9 | |
| SCHEMBL11233309 | 0.76 | TSHR (0.52) | CNR2SLC6A9TSHRIRAK4 | |
| SCHEMBL5306302 | 0.75 | SLC6A2 (0.68) | SLC6A2SLC6A4NOS2CYP2D6SLC6A9 | |
| Oxalic Acid SCHEMBL4936002 | 0.75 | SLC6A2 (0.59) | SLC6A2SLC6A4NOS2CYP2D6SLC6A9 | |
| Hydrochloric Acid SCHEMBL7306045 | 0.74 | SLC6A2 (0.68) | SLC6A2SLC6A4NOS2CYP2D6SLC6A9 | |
| Oxalic Acid SCHEMBL7317717 | 0.73 | SLC6A2 (0.60) | SLC6A2SLC6A4NOS2CYP2D6SLC6A3 | |
| Phenyl Propionic Acid SCHEMBL11232741 | 0.73 | KEAP1 (0.45) | SLC6A2SLC6A4NOS2CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313896-A | ANTIDEPRESSANTS, PSYCHOTROPIC AGENTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | disclosed |