Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039494 | 0.91 | ALDH1A1 (0.58) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30062 | 0.91 | ALDH1A1 (0.58) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27700835 | 0.89 | ALDH1A1 (0.56) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Bromide SCHEMBL7641961 | 0.89 | ALDH1A1 (0.56) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Iodide SCHEMBL27448064 | 0.89 | ALDH1A1 (0.56) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3656248 | 0.89 | ALDH1A1 (0.56) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27474934 | 0.86 | ALDH1A1 (0.54) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3305633 | 0.85 | HPGD (0.62) | HPGDRAB9ANPC1ALDH1A1SRD5A2 | |
| SCHEMBL14736324 | 0.84 | ALDH1A1 (0.52) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| Benzophenone SCHEMBL27422465 | 0.84 | ALDH1A1 (0.78) | HPGDRAB9ANPC1ALDH1A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347383-A | BY REACTING BENZOPHENONE-IMINE WITH OXYGEN OR BENZOPHENONE WITH OXYGEN AND AMMONIA | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1982-08-31 | — | — | US | disclosed |