Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Hydrochloric Acid SCHEMBL27700835 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Hydrochloric Acid SCHEMBL3656248 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Iodide SCHEMBL27448064 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Bromide SCHEMBL7641961 | 0.97 | ALDH1A1 (0.56) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| SCHEMBL27474934 | 0.95 | ALDH1A1 (0.54) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| SCHEMBL14736324 | 0.93 | ALDH1A1 (0.52) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Toluene SCHEMBL27540980 | 0.91 | CES2 (0.54) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Hydrogen Sulfide SCHEMBL10651079 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT | |
| Dimethylamine SCHEMBL28215588 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HPGDSMN1; SMN2HSD11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | disclosed |