Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941803 | 0.87 | ACHE (0.53) | SIGMAR1ACHEBCHE | |
| SCHEMBL3941806 | 0.87 | ACHE (0.53) | SIGMAR1ACHEBCHE | |
| SCHEMBL3943931 | 0.87 | ACHE (0.53) | SIGMAR1ACHEBCHE | |
| SCHEMBL11221703 | 0.85 | FUCA1 (0.46) | FUCA1SIGMAR1ACHEMC4RS1PR1 | |
| SCHEMBL9688491 | 0.83 | ACHE (0.60) | SIGMAR1ACHEMC4RBCHE | |
| SCHEMBL11234628 | 0.81 | FUCA1 (0.45) | FUCA1SIGMAR1ACHEMC4RS1PR1 | |
| SCHEMBL22593919 | 0.78 | FUCA1 (0.61) | FUCA1SIGMAR1ACHEMC4RS1PR1 | |
| SCHEMBL20901984 | 0.77 | FUCA1 (0.60) | FUCA1SIGMAR1ACHEMC4RS1PR1 | |
| SCHEMBL10041956 | 0.77 | FUCA1 (0.60) | FUCA1SIGMAR1ACHEMC4RS1PR1 | |
| SCHEMBL16080228 | 0.77 | FUCA1 (0.60) | FUCA1SIGMAR1ACHEMC4RS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | claimed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |