Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943931 | 1.00 | ACHE (0.53) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL3941803 | 1.00 | ACHE (0.53) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL9688491 | 0.91 | ACHE (0.60) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL11233396 | 0.87 | FUCA1 (0.50) | ACHEBCHESIGMAR1 | |
| SCHEMBL3271398 | 0.83 | LTA4H (0.60) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL4512639 | 0.83 | LTA4H (0.60) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL18038825 | 0.81 | LTA4H (0.58) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL1804779 | 0.80 | ACHE (0.48) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL1235952 | 0.80 | ACHE (0.48) | ACHEBCHEBACE1SMN1; SMN2GAA | |
| SCHEMBL2614397 | 0.80 | ACHE (0.54) | ACHEBCHEBACE1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011551-A2 | PROCESS FOR THE EFFICIENT PREPARATION OF 3-HYDROXY PYRROLIDINE AND DERIVATIVES THEREOF | RSTECH CORPORATION (KR) | 2009-01-22 | — | — | WO | disclosed |