Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349904 | 0.83 | POLB (0.66) | POLBABCG2NR4A2LMNAKMT2A | |
| SCHEMBL2538347 | 0.83 | ABCG2 (0.57) | POLBABCG2NR4A2LMNAKMT2A | |
| SCHEMBL2538344 | 0.83 | ABCG2 (0.57) | POLBABCG2NR4A2LMNAKMT2A | |
| SCHEMBL7283987 | 0.82 | NR4A2 (0.64) | POLBABCG2NR4A2LMNAKMT2A | |
| Fumaric Acid SCHEMBL7316800 | 0.81 | HTR3A (0.53) | POLBABCG2NR4A2LMNAKMT2A | |
| Maleic Acid SCHEMBL7316790 | 0.81 | HTR3A (0.53) | POLBABCG2NR4A2LMNAKMT2A | |
| SCHEMBL29965768 | 0.81 | POLB (0.72) | POLBNR4A2LMNAKMT2AMAPT | |
| SCHEMBL535878 | 0.81 | POLB (0.72) | POLBNR4A2LMNAKMT2AMAPT | |
| SCHEMBL10781557 | 0.80 | ABCG2 (0.57) | POLBABCG2NR4A2LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2434452 | 0.80 | POLB (0.70) | POLBNR4A2LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342689-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342690-A | HHYPOTENSIVE AGE TS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4342691-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4299769-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-11-10 | — | — | US | disclosed |