SCHEMBL11233451

SCHEMBL11233451

CC(C)OC1=C([PH](c2ccccc2)(c2ccccc2)c2ccccc2)CCC1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
CHRNB4 P30926 2/20 0.30
CHRNA3 P32297 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11144704 0.98 ALDH1A1 (0.32) ALDH1A1LMNAHPGDTSHR
SCHEMBL11228438 0.97 ALDH1A1 (0.32) ALDH1A1LMNAHPGDTSHRCHRNB4
SCHEMBL11234291 0.95 ALDH1A1 (0.32) ALDH1A1LMNAHPGDTSHR
Iodide SCHEMBL11137509 0.94 ALDH1A1 (0.31) ALDH1A1LMNAHPGDTSHR
SCHEMBL11227955 0.81 EGFR (0.33)
SCHEMBL11142208 0.77 CA4 (0.32)
SCHEMBL11245133 0.76 CA4 (0.31)
SCHEMBL11227711 0.72 MAOB (0.39) LMNATSHRL3MBTL1MAPT
SCHEMBL11236301 0.70 KDM1A (0.30)
SCHEMBL11236299 0.70 CACNA1B (0.33) ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4336252-A 1-Cycloalkyl phosphonium salts G. D. SEARLE & CO. (US) 1982-06-22 US claimed