Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238564 | 0.89 | ALDH1A1 (0.47) | CYP11B1CYP11B2ALDH1A1HMOX2CYP19A1 | |
| SCHEMBL11246282 | 0.84 | EGLN3 (0.54) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11238995 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP11B2ALDH1A1HMOX2CYP19A1 | |
| SCHEMBL11245838 | 0.83 | CYP11B1 (0.60) | CYP11B1CYP11B2ALDH1A1HMOX2 | |
| SCHEMBL7241523 | 0.78 | ALDH1A1 (0.72) | ALDH1A1HMOX2CYP19A1ALPIALPG | |
| SCHEMBL11237322 | 0.78 | CYP11B1 (0.59) | CYP11B1CYP11B2ALDH1A1HMOX2CYP19A1 | |
| SCHEMBL11248355 | 0.78 | CYP19A1 (0.59) | CYP11B1CYP11B2ALDH1A1HMOX2CYP19A1 | |
| SCHEMBL11370807 | 0.77 | ALDH1A1 (0.55) | CYP11B1CYP11B2ALDH1A1CYP19A1ALPI | |
| SCHEMBL4288375 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HMOX2CYP19A1 | |
| SCHEMBL11250406 | 0.75 | EGLN3 (0.50) | CYP11B1CYP11B2ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |