Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 12/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250406 | 0.90 | EGLN3 (0.50) | EGLN3CYP11B1CYP11B2TBXAS1MEN1 | |
| SCHEMBL11233475 | 0.84 | CYP11B1 (0.57) | CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11241105 | 0.84 | CYP11B1 (0.57) | EGLN3CYP11B1CYP11B2TBXAS1MEN1 | |
| SCHEMBL11236348 | 0.79 | CYP19A1 (0.56) | EGLN3CYP11B1CYP11B2TBXAS1ALDH1A1 | |
| SCHEMBL11244197 | 0.79 | CYP11B1 (0.56) | EGLN3CYP11B1CYP11B2TBXAS1MEN1 | |
| SCHEMBL11253132 | 0.78 | EGLN3 (0.50) | EGLN3TBXAS1MEN1KMT2A | |
| SCHEMBL11256842 | 0.78 | EGLN3 (0.50) | EGLN3TBXAS1MEN1KMT2AALDH1A1 | |
| SCHEMBL11264399 | 0.77 | CYP11B1 (0.58) | EGLN3CYP11B1CYP11B2TBXAS1MEN1 | |
| SCHEMBL10780853 | 0.77 | EGLN3 (0.65) | EGLN3TBXAS1ALDH1A1 | |
| SCHEMBL47382 | 0.77 | EGLN3 (0.69) | EGLN3TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |