Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cicloxilic Acid SCHEMBL866481 | 1.00 | CNR2 (0.46) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| Cicloxilic Acid SCHEMBL30436810 | 1.00 | CNR2 (0.46) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| Cicloxilic Acid SCHEMBL866482 | 1.00 | CNR2 (0.46) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| SCHEMBL27677680 | 0.85 | KMT2A (0.58) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| SCHEMBL27593652 | 0.83 | KMT2A (0.43) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| SCHEMBL10631400 | 0.81 | LMNA (0.40) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| SCHEMBL3314911 | 0.77 | CNR2 (0.41) | CNR2CNR1AKR1C1ALDH1A1MAPT | |
| SCHEMBL1852711 | 0.77 | CNR2 (0.42) | CNR2CNR1AKR1C1OPRM1OPRL1 | |
| SCHEMBL6933056 | 0.77 | CNR2 (0.42) | CNR2CNR1AKR1C1OPRM1OPRL1 | |
| SCHEMBL6543483 | 0.77 | CNR2 (0.42) | CNR2CNR1AKR1C1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125558-A | Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid | GUIDOTTI INTERNATIONALE S.A. (IT) | 1978-11-14 | — | — | US | claimed |
| US-4336398-A | Process for the preparation of basic esters of substituted hydroxycyclohexanecarboxylic acids | LABORATORIO GUIDOTTI & C. S.P.A. (IT) | 1982-06-22 | — | — | US | disclosed |
| US-4125558-A | Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid | GUIDOTTI INTERNATIONALE S.A. (IT) | 1978-11-14 | — | — | US | disclosed |
| US-4125558-A | Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid | GUIDOTTI INTERNATIONALE S.A. (IT) | 1978-11-14 | — | — | US | disclosed |
| US-4125558-A | Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid | GUIDOTTI INTERNATIONALE S.A. (IT) | 1978-11-14 | — | — | US | disclosed |