Cicloxilic Acid

Cicloxilic Acid

SCHEMBL866482

O=C(O)C1CCCCC1(O)c1ccccc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 7/20 0.46
CNR1 P21554 3/20 0.46
AKR1C1 Q04828 1/20 0.46
ALDH1A1 P00352 2/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 2/20 0.44
HDAC4 P56524 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
OPRM1 P35372 3/20 0.41
OPRL1 P41146 3/20 0.41
SLC6A9 P48067 3/20 0.41
SLC6A5 Q9Y345 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cicloxilic Acid SCHEMBL866481 1.00 CNR2 (0.46) CNR2CNR1AKR1C1ALDH1A1MAPT
Cicloxilic Acid SCHEMBL30436810 1.00 CNR2 (0.46) CNR2CNR1AKR1C1ALDH1A1MAPT
Cicloxilic Acid SCHEMBL11233561 1.00 CNR2 (0.46) CNR2CNR1AKR1C1ALDH1A1MAPT
SCHEMBL27677680 0.85 KMT2A (0.58) CNR2CNR1AKR1C1ALDH1A1MAPT
SCHEMBL27593652 0.83 KMT2A (0.43) CNR2CNR1AKR1C1ALDH1A1MAPT
SCHEMBL10631400 0.81 LMNA (0.40) CNR2CNR1AKR1C1ALDH1A1MAPT
SCHEMBL3314911 0.77 CNR2 (0.41) CNR2CNR1AKR1C1ALDH1A1MAPT
SCHEMBL1852711 0.77 CNR2 (0.42) CNR2CNR1AKR1C1OPRM1OPRL1
SCHEMBL6933056 0.77 CNR2 (0.42) CNR2CNR1AKR1C1OPRM1OPRL1
SCHEMBL6543483 0.77 CNR2 (0.42) CNR2CNR1AKR1C1OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20110117194-A1 PHARMACEUTICAL FORMULATION CONTAINING ANGIOTENSIN-II RECEPTOR BLOCKER HANALL BIOPHARMA CO., LTD. (KR) 2011-05-19 US claimed
CN-102065847-A Pharmaceutical formulation containing angiotensin-II receptor blocker HANALL PHARMACEUTICAL CO LTD 2011-05-18 CN claimed
EP-2281557-A2 PHARMACEUTICAL FORMULATION CONTAINING ANGIOTENSIN-II RECEPTOR BLOCKER HanAll Biopharma Co., Ltd. (KR) 2011-02-09 EP claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
CN-1443575-A Medicine for curing metabolic syndrome LIAONING YILIAN NEW MEDICINE I (CN) 2003-09-24 CN claimed
CN-1433766-A Medicine for treating metabolism syndrome LIAONING YILIAN NOVEL MEDICINE (CN) 2003-08-06 CN claimed
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US claimed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP disclosed
US-20220047505-A1 Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration STI PHARMA, LLC (US) 2022-02-17 US disclosed
US-11191719-B2 Controlled absorption water-soluble pharmaceutically active organic compound formulation for once-daily administration STI PHARMA, LLC (US) 2021-12-07 US disclosed
CN-108069846-B Method for resolving cis-1-hydroxy- [1,1' -bis (cyclohexyl) ] -2-formic acid and intermediate 上海医药工业研究院 2020-11-03 CN disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US disclosed
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US disclosed