Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PLK1 | P53350 | 5/20 | 0.55 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123169 | 0.91 | SENP7 (0.61) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL1123608 | 0.91 | SENP7 (0.61) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL1123204 | 0.85 | SENP7 (0.65) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL1123607 | 0.80 | SENP7 (0.61) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL1123026 | 0.80 | SMPD1 (0.59) | SENP7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1123323 | 0.78 | PLK1 (0.64) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL9347607 | 0.78 | SENP7 (0.66) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL19831686 | 0.77 | SENP7 (0.79) | SENP7SENP8SENP6NPC1RAB9A | |
| SCHEMBL2294814 | 0.76 | SENP7 (0.74) | SENP7SENP8SENP6MEN1KMT2A | |
| SCHEMBL1464667 | 0.76 | PLK1 (0.90) | MEN1KMT2APLK1PLK3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |