Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123204 | 0.93 | SENP7 (0.65) | PLK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL5936643 | 0.88 | SMN1; SMN2 (0.61) | PLK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL5936652 | 0.87 | NPC1 (0.62) | PLK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL9347607 | 0.85 | SENP7 (0.66) | PLK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL9351304 | 0.85 | SMN1; SMN2 (0.63) | NPC1RAB9ASMN1; SMN2SENP7CASP3 | |
| SCHEMBL9348945 | 0.85 | PPARA (0.58) | PLK1NPC1RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL1123096 | 0.84 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123501 | 0.83 | L3MBTL1 (0.63) | NPC1RAB9ASMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123418 | 0.83 | NR1H4 (0.65) | NPC1RAB9ASMN1; SMN2SENP7CASP3 | |
| SCHEMBL1122992 | 0.83 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2SENP7CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |