Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11235978 | 0.91 | KMT2A (0.52) | EGFRCACNA1BMMP1MMP2MMP9 | |
| SCHEMBL28158149 | 0.84 | EGFR (0.57) | EGFRCACNA1BMMP1MMP2MMP9 | |
| SCHEMBL28894463 | 0.84 | EGFR (0.57) | EGFRCACNA1BMMP1MMP2MMP9 | |
| SCHEMBL7672671 | 0.79 | CYP3A4 (0.56) | EGFRALDH1A1MAPTCSNK2A1KLF10 | |
| SCHEMBL11229669 | 0.78 | MMP1 (0.52) | EGFRCACNA1BL3MBTL1MMP1MMP2 | |
| SCHEMBL5695937 | 0.77 | TDP1 (0.67) | EGFRL3MBTL1ALDH1A1TDP1CSNK2A1 | |
| SCHEMBL1129358 | 0.76 | CYP3A4 (0.57) | EGFRCACNA1BMMP1MMP2MMP9 | |
| SCHEMBL1641611 | 0.76 | CA12 (0.74) | EGFRALDH1A1MAPTSMN1; SMN2CSNK2A1 | |
| SCHEMBL5132344 | 0.75 | HSD17B2 (0.59) | EGFRCACNA1BALDH1A1MAPTRECQL | |
| SCHEMBL5132345 | 0.75 | HSD17B2 (0.59) | EGFRCACNA1BALDH1A1MAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317917-A | ANTIINFLAMMATORY, ANALGESIC, ANTIBACTERIAL | AUSONIA FARMACEUTICI S.R.L. (IT) | 1982-03-02 | — | — | US | disclosed |